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Severe Cannabis/THC Allergy - 6 week update

Here is a link to the last thread I made, it's very long and has the full history of my symptoms. I'll sum up the important points in this thread. Thank you again to everyone that posted in there, I really appreciate the feedback. It's been about a year now that the reaction is so bad that smoking isn't worth it, and I really want to get through this and find a way to smoke without my body trying to kill me. My quality of life, physical health, and anxiety have all been effected by this.
http://www.reddit.com/DrugNerds/comments/1s3gnw/cannabis_allergyautoimmune_troubles_looking_fo
Here's a recap on the symptoms and the things I've tried:
The reaction:
No wheezing or decreased lung capacity, but immediately after getting high I have difficulty breathing because thick mucus/phlegm is continually pooling in the back of my throat. It’s white so it’s unlikely I have any sort of infection….just an immune response I imagine. I spit it out and spit it out, but it just seems to keep coming. The thicker the mucus, the more trouble I have breathing...if I take Mucinex and do a sinus rinse before smoking and drink herbal tea and eat raw garlic/ginger afterwards its a bit better, but still not great. It seems I can expect to be spitting this stuff out at least once every 5-10 mins for a good 12 hours. Aside from this I have decreased appetite, and some stomach pain. I used to have bloating and urine retention problems but taking probiotics seems to have helped with that.
Oddly enough I also seem to get muscle pain in my lower back and sometimes shoulders from smoking, especially if I'm really high.. If my posture isn’t absolutely perfect then I’m in a lot of pain, I've even had my hands trembling once before.
Things I have tried (that failed):
Things I am considering trying
Update
Unfortunately, I'm still having some troubles. Since my last post I went another few weeks without smoking at all, but then a trusted friend came through with some of what he told me was the cleanest BHO he has ever made, so I gave that a try. The first time I tried it I did a sinus rinse before hand and tried to get as much mucus out as possible, since if I DO have the reaction it will get very thick and give me trouble breathing.
I tried a very small amount of the BHO and got higher than I've been in a year, it was nice for an hour or so, but then the reaction started to come on a bit stronger. Still it wasn't too bad, it was nice being high again.
The next day however I had more mucus/post-nasal drip than usual, and I tried smoking again (before doing a sinus rinse) and I realized immediately that it was a terrible mistake. I ended up standing in a hot shower for an hour trying to use steam to thin mucus so I could breathe. I probably should have used my epi pen and/or gone to the hospital...it got pretty scary.
So, I think this rules out the allergy being to the plant material. It looks like it may be an actual Cannabinoid, maybe THC? I came across a study published two weeks ago by the Indian Journal of Allergy, Asthma, and Immunology about Cannabis allergy. It's mostly about pollenation troubles but it discusses how some people can have a THC allergy, here's the study: http://www.ijaai.in/article.asp?issn=0972-6691;year=2013;volume=27;issue=2;spage=143;epage=146;aulast=Kumar
Does anyone know where I could go to receive testing and then immunotherapy for an IgE specific Cannabis/THC? allergy? I'm starting to think that's my best option, but I've looked into it and I can't find any answers. The allergist I used to go to wasn't very helpful at all. I live in Baltimore, but would be more than happy to go to Colorado or Washington or somewhere like that if they offered such a thing. I feel like someone, somewhere has to be doing this...it would raise my quality of life so much if I could just get rid of this allergy.
Again, if you actually read through all of that I'm very thankful, this is an awesome community. If anyone is able to give me any helpful advice or point me to a study I could sign up for I'd gladly send some bitcoins your way.
submitted by theworstallergy to DrugNerds [link] [comments]

Cannabis allergy/autoimmune troubles, looking for advice

I made this post in /drugs yesterday and didn't get much of a response, but was told this may be a better subreddit for it.
Foreword: This is a lot of text, enough to warrant a foreword. I don’t actually expect everyone to read this whole thing, but I wanted to be as thorough as possible in case someone does think they can offer any advice, and because this has been bothering me for a long time now. I will happily, happily send bitcoins to anyone who is able to help me out here, even if you can just point me to a person or resource that COULD be more helpful.
Also please don’t post an ignorant response along the lines of “weed is good for you, you can’t be allergic to it”. I love weed, it has helped with my anxiety and increased my quality of life quite a bit over the past few years and I miss it a lot, which is the whole reason I’m posting this. I realize my situation is very rare, but clearly people CAN have negative physical reactions to it.
Timeline:
24+ months ago: I had no health problems or history of health problems at this point. I had probably smoked weed a dozen or two times in my life and was physically fit and active. My weight hasn’t changed at any point in all of this, I’m about 6’0” 165 lbs, white male. I was 22 then, 24 now.
12-24 months ago: I started smoking with friends around this time, and this is when I started to notice something wasn’t quite right. I would experience a bit of wheezing some of the times I smoked with friends, they thought it was weird but no one thought much of it. I thought it was strange too since I hadn’t experienced it the other times I’d smoked, and at first I thought I may just be sensitive to smoke in my lungs or heat or something along those lines, so I bought my first vaporizer and started smoking on my own here and there. On average during this time period I probably smoked 2-4 times a week, usually at night.
As time went on the wheezing started to happen EVERY time that I smoked. I would buy Ricola cough drops and always suck on one as I vaped, since it seemed to help a bit, but then it got to the point where I was experiencing wheezing for a day or two after smoking, as well as anytime I went for a run. After a month or two of this I had what I suppose you could call an asthma attack after taking a big hit, I had a lot of trouble breathing and it scared me quite a bit. The next day I was wheezing very badly so I went to a Patient First (Urgent Care center in the US) and they gave me a rescue inhaler and set me up with an appointment with an allergist.
6-12 Months ago: I had my first appointment with the allergist and was completely up front with him about everything. Honestly, this guy was pretty cool. I told him I thought I was allergic to weed and he told me I could eat it but not to smoke it anymore. Later that week I made a batch of brownies with some friends and gave it a shot and unfortunately, it didn’t go so well. I’m not exaggerating when I say that I almost died, I used my rescue inhaler far more times than you’re supposed to and the night ended with me laying outside gasping for fresh air. Not a pleasant experience for anyone involved, I felt bad for my friends for having to deal with that on an otherwise really pleasant night.
I told the allergist about this the next time I saw him and he was surprised, he said he had never heard of someone actually being allergic to cannabis in his 20 years of experience. I asked him what my options were, if there was anything that I could do to stop the reaction, be it before, during, or after smoking, and he told me there really wasn’t much. He could start me on Immunization shots if they existed, but cannabis is illegal and not a common allergy so they don’t. He said caffeine could help with Asthma so I started drinking coffee every morning. He recommended that I stop smoking at this point and gave me a prescription for Singulair and a nasal spray, so I started taking those every day as well as antihistamines. It’s worth noting that I started having other allergies at this point too (previously I had none). Weed was the only one that gave me asthma symptoms but dust mites and mold would also bother me.
I did a lot of experimenting with different things that could help around this time, you can read about them below. Unfortunately, none really worked. Oh, I also started doing daily sinus rinses around this time since I got a couple of sinus infections (another first). I was still smoking around 2-4 times a week, sometimes with friends and sometimes by myself, but every time now I would have to use my inhaler at least once. Time passed with more failed personal experiments and the reaction was getting stronger, on my next appointment with the allergist (again, I was completely honest with him about everything) he put me on another asthma control medicine called Advair, so I started taking this twice daily along with the others. Honestly, it improved things a bit, I was even able to smoke with friends a couple of times without using an inhaler, but time passed and I continued to smoke, and it continued to get worse.
2-6 Months ago
I started to train for a Tough Mudder (12 mile run + obstacle course) around this time and decided it would be best to quit smoking for a couple of weeks prior to make sure I could complete it and not embarrass myself in front of the coworkers and friends I was running with. Fortunately I didn’t, I completed it and the next day tried to smoke hoping things would be better, but they weren’t. This is the point in time that the reaction changed. I haven’t really experienced any wheezing or asthma symptoms since then, the reaction has changed to what you’d expect with GERD (acid reflux). I didn’t really know what this was at the time (aside from hearing about its name on commercials), but after describing my new symptoms from smoking to my allergist and having peak flow meter and spirometry tests done he said I really wasn’t having asthma problems anymore, the asthma is well controlled. He referred me to a GI Specialist.
I had one more appointment with him and tried the last thing that could possible help. He started me on Xolair, which I was hesitant to try at first due to possible side effects. It’s a drug that is injected once a month that can help with allergic asthma and other immune problems. Unfortunately after two injections I noticed it was making my hair thin out rapidly and didn’t seem to be doing much (It should have been working by then) so I stopped taking it.
I saw the GI Specialist, told him about the acid reflux problems and the cannabis reaction. Honestly, this doctor was shit. I feel like he didn’t listen to a word I said, but he requested an endoscopy be performed so I went through with it and he told me he didn’t see much wrong (but he did say I have Gastritis in my stomach). He recommended I take a course of Prilosec and stop smoking. By this point I only smoked once or twice a week because it was getting pretty bad. I couldn’t smoke with friends anymore since every time I got high I’d have to start spitting thick mucus into a cup and it was pretty embarrassing and disgusting. I stopped drinking coffee and started adjusting my diet to be as healthy as possible to get over the reflux, (though still hasn’t quite happened)
The past 2 months: The past 2 months have been shit, I’ve honestly been pretty depressed. It took 2 years but it’s finally hit the point where it is no longer worth it for me to smoke. It’s probably been like that for a while really and I was just in denial, but I can admit that the reaction is so bad that the cons outweigh the pros at this point. Being high just isn't a pleasant experience anymore. I've experienced a lot more anxiety lately and am starting to think I won’t see a solution to this, or at least not anytime soon. I’ve experimented with smoking herbal blends (white sage, mullein, damiana, blue lotus, etc) but it’s not nearly the same. I've been trying to meditate and exercise often and it helps, but I just don’t enjoy life as much as I used to when I knew I could smoke with my friends if I wanted to. I don’t even hang out with them as much now since I can’t smoke and it can get a bit awkward if that's what they're going to be doing. I went 5-6 weeks without smoking recently and gave it a go for the first time last Saturday hoping things would be better, but they were just as bad as ever.
Here’s what the reaction is now:
No wheezing or decreased lung capacity, but immediately after getting high I have difficulty breathing because thick mucus/phlegm is continually pooling in the back of my throat. It’s white so it’s unlikely I have any sort of infection….just an immune response I imagine. I spit it out and spit it out, but it just seems to keep coming. It seems I can expect to be spitting this stuff out at least once every 5-10 mins for a good 12 hours. Aside from this I have decreased appetite, some stomach pain, and eventually bloating/urine retention and abdominal pain. Oddly enough I also seem to get a lot of lower back pain now if I smoke. If my posture isn’t absolutely perfect then I’m in a lot of pain.
Right now I’ve decided I’m done smoking until my acid reflux/stomach problems have resolved themselves…I won’t try again until that happens or I come across another suggestion that might work.
Things I have tried (that failed):
Things I am currently doing (mostly to help with acid reflux/GERD problems):
Things I have considered, but not tried:
If anyone actually read all of this and/or has has any kind of advice it would be much appreciated. Even if you just have another casual drug that you’d suggest that I may like. I’ve tried shrooms and LSD a handful of times and had great experiences, but those (to me) are the kind of thing you do once a month tops. I’m not a huge fan of alcohol, it doesn’t do much for me. I really miss the introspection that weed brought me, as well as the reduction in anxiety and just calm, chillout feeling. Anything similar to it would be much appreciated.
submitted by theworstallergy to DrugNerds [link] [comments]

Cannabis allergy/autoimmune troubles, looking for advice

Foreword: This is a lot of text, enough to warrant a foreword. I don’t actually expect everyone to read this whole thing, but I wanted to be as thorough as possible in case someone does think they can offer any advice, and because this has been bothering me for a long time now. I will happily, happily send bitcoins to anyone who is able to help me out here, even if you can just point me to a person or resource that COULD be more helpful.
Also please don’t post an ignorant response along the lines of “weed is good for you, you can’t be allergic to it”. I love weed, it has helped with my anxiety and increased my quality of life quite a bit over the past few years and I miss it a lot, which is the whole reason I’m posting this. I realize my situation is very rare, but clearly people CAN have negative physical reactions to it.
Timeline:
24+ months ago: I had no health problems or history of health problems at this point. I had probably smoked weed a dozen or two times in my life and was physically fit and active. My weight hasn’t changed at any point in all of this, I’m about 6’0” 165 lbs, white male. I was 22 then, 24 now.
12-24 months ago: I started smoking with friends around this time, and this is when I started to notice something wasn’t quite right. I would experience a bit of wheezing some of the times I smoked with friends, they thought it was weird but no one thought much of it. I thought it was strange too since I hadn’t experienced it the other times I’d smoked, and at first I thought I may just be sensitive to smoke in my lungs or heat or something along those lines, so I bought my first vaporizer and started smoking on my own here and there. On average during this time period I probably smoked 2-4 times a week, usually at night.
As time went on the wheezing started to happen EVERY time that I smoked. I would buy Ricola cough drops and always suck on one as I vaped, since it seemed to help a bit, but then it got to the point where I was experiencing wheezing for a day or two after smoking, as well as anytime I went for a run. After a month or two of this I had what I suppose you could call an asthma attack after taking a big hit, I had a lot of trouble breathing and it scared me quite a bit. The next day I was wheezing very badly so I went to a Patient First (Urgent Care center in the US) and they gave me a rescue inhaler and set me up with an appointment with an allergist.
6-12 Months ago: I had my first appointment with the allergist and was completely up front with him about everything. Honestly, this guy was pretty cool. I told him I thought I was allergic to weed and he told me I could eat it but not to smoke it anymore. Later that week I made a batch of brownies with some friends and gave it a shot and unfortunately, it didn’t go so well. I’m not exaggerating when I say that I almost died, I used my rescue inhaler far more times than you’re supposed to and the night ended with me laying outside gasping for fresh air. Not a pleasant experience for anyone involved, I felt bad for my friends for having to deal with that on an otherwise really pleasant night.
I told the allergist about this the next time I saw him and he was surprised, he said he had never heard of someone actually being allergic to cannabis in his 20 years of experience. I asked him what my options were, if there was anything that I could do to stop the reaction, be it before, during, or after smoking, and he told me there really wasn’t much. He could start me on Immunization shots if they existed, but cannabis is illegal and not a common allergy so they don’t. He said caffeine could help with Asthma so I started drinking coffee every morning. He recommended that I stop smoking at this point and gave me a prescription for Singulair and a nasal spray, so I started taking those every day as well as antihistamines. It’s worth noting that I started having other allergies at this point too (previously I had none). Weed was the only one that gave me asthma symptoms but dust mites and mold would also bother me.
I did a lot of experimenting with different things that could help around this time, you can read about them below. Unfortunately, none really worked. Oh, I also started doing daily sinus rinses around this time since I got a couple of sinus infections (another first). I was still smoking around 2-4 times a week, sometimes with friends and sometimes by myself, but every time now I would have to use my inhaler at least once. Time passed with more failed personal experiments and the reaction was getting stronger, on my next appointment with the allergist (again, I was completely honest with him about everything) he put me on another asthma control medicine called Advair, so I started taking this twice daily along with the others. Honestly, it improved things a bit, I was even able to smoke with friends a couple of times without using an inhaler, but time passed and I continued to smoke, and it continued to get worse.
2-6 Months ago
I started to train for a Tough Mudder (12 mile run + obstacle course) around this time and decided it would be best to quit smoking for a couple of weeks prior to make sure I could complete it and not embarrass myself in front of the coworkers and friends I was running with. Fortunately I didn’t, I completed it and the next day tried to smoke hoping things would be better, but they weren’t. This is the point in time that the reaction changed. I haven’t really experienced any wheezing or asthma symptoms since then, the reaction has changed to what you’d expect with GERD (acid reflux). I didn’t really know what this was at the time (aside from hearing about its name on commercials), but after describing my new symptoms from smoking to my allergist and having peak flow meter and spirometry tests done he said I really wasn’t having asthma problems anymore, the asthma is well controlled. He referred me to a GI Specialist.
I had one more appointment with him and tried the last thing that could possible help. He started me on Xolair, which I was hesitant to try at first due to possible side effects. It’s a drug that is injected once a month that can help with allergic asthma and other immune problems. Unfortunately after two injections I noticed it was making my hair thin out rapidly and didn’t seem to be doing much (It should have been working by then) so I stopped taking it.
I saw the GI Specialist, told him about the acid reflux problems and the cannabis reaction. Honestly, this doctor was shit. I feel like he didn’t listen to a word I said, but he requested an endoscopy be performed so I went through with it and he told me he didn’t see much wrong (but he did say I have Gastritis in my stomach). He recommended I take a course of Prilosec and stop smoking. By this point I only smoked once or twice a week because it was getting pretty bad. I couldn’t smoke with friends anymore since every time I got high I’d have to start spitting thick mucus into a cup and it was pretty embarrassing and disgusting. I stopped drinking coffee and started adjusting my diet to be as healthy as possible to get over the reflux, (though still hasn’t quite happened)
The past 2 months: The past 2 months have been shit, I’ve honestly been pretty depressed. It took 2 years but it’s finally hit the point where it is no longer worth it for me to smoke. It’s probably been like that for a while really and I was just in denial, but I can admit that the reaction is so bad that the cons outweigh the pros at this point. Being high just isn't a pleasant experience anymore. I've experienced a lot more anxiety lately and am starting to think I won’t see a solution to this, or at least not anytime soon. I’ve experimented with smoking herbal blends (white sage, mullein, damiana, blue lotus, etc) but it’s not nearly the same. I've been trying to meditate and exercise often and it helps, but I just don’t enjoy life as much as I used to when I knew I could smoke with my friends if I wanted to. I don’t even hang out with them as much now since I can’t smoke and it can get a bit awkward if that's what they're going to be doing. I went 5-6 weeks without smoking recently and gave it a go for the first time last Saturday hoping things would be better, but they were just as bad as ever.
Here’s what the reaction is now:
No wheezing or decreased lung capacity, but immediately after getting high I have difficulty breathing because thick mucus/phlegm is continually pooling in the back of my throat. It’s white so it’s unlikely I have any sort of infection….just an immune response I imagine. I spit it out and spit it out, but it just seems to keep coming. It seems I can expect to be spitting this stuff out at least once every 5-10 mins for a good 12 hours. Aside from this I have decreased appetite, some stomach pain, and eventually bloating/urine retention and abdominal pain. Oddly enough I also seem to get a lot of lower back pain now if I smoke. If my posture isn’t absolutely perfect then I’m in a lot of pain.
Right now I’ve decided I’m done smoking until my acid reflux/stomach problems have resolved themselves…I won’t try again until that happens or I come across another suggestion that might work.
Things I have tried (that failed):
Things I am currently doing (mostly to help with acid reflux/GERD problems): Taking probiotics every day
Things I have considered, but not tried:
If anyone actually read all of this and/or has has any kind of advice it would be much appreciated. Even if you just have another casual drug that you’d suggest that I may like. I’ve tried shrooms and LSD a handful of times and had great experiences, but those (to me) are the kind of thing you do once a month tops. I’m not a huge fan of alcohol, it doesn’t do much for me. I really miss the introspection that weed brought me, as well as the reduction in anxiety and just calm, chillout feeling. Anything similar to it would be much appreciated.
submitted by theworstallergy to Drugs [link] [comments]

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Bitcoin basics: What is the difficulty target and how does it adjust itself?

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